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Structure paper

TitleStructural Mimicry of Receptor Interaction by Antagonistic Interleukin-6 (IL-6) Antibodies.
Journal, issue, pagesJ. Biol. Chem., Vol. 291, Page 13846-13854, Year 2016
Publish dateMay 13, 2015 (structure data deposition date)
AuthorsBlanchetot, C. / De Jonge, N. / Desmyter, A. / Ongenae, N. / Hofman, E. / Klarenbeek, A. / Sadi, A. / Hultberg, A. / Kretz-Rommel, A. / Spinelli, S. ...Blanchetot, C. / De Jonge, N. / Desmyter, A. / Ongenae, N. / Hofman, E. / Klarenbeek, A. / Sadi, A. / Hultberg, A. / Kretz-Rommel, A. / Spinelli, S. / Loris, R. / Cambillau, C. / de Haard, H.
External linksJ. Biol. Chem. / PubMed:27129274
MethodsX-ray diffraction
Resolution2.93 Å
Structure data

PDB-4zs7:
Structural mimicry of receptor interaction by antagonistic IL-6 antibodies
Method: X-RAY DIFFRACTION / Resolution: 2.93 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • lama glama (llama)
KeywordsIMMUNE SYSTEM / Interleukine 6 Complex / Fab fragment / Dromedery

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