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TitleTwo mutations G335D and Q343R within the amyloidogenic core region of TDP-43 influence its aggregation and inclusion formation
Journal, issue, pagesSci Rep, Vol. 6, Page 23928-23928, Year 2016
Publish dateJun 11, 2015 (structure data deposition date)
AuthorsJiang, L.L. / Zhao, J. / Yin, X.F. / He, W.T. / Yang, H. / Che, M.X. / Hu, H.Y.
External linksSci Rep / PubMed:27030292
MethodsNMR (solution)
Structure data

PDB-2n3x:
Solution Structure of TDP-43 Amyloidogenic Core Region
Method: SOLUTION NMR

PDB-2n4g:
Solution Structure of the G335D Mutant of TDP-43 Amyloidogenic Core Region
Method: SOLUTION NMR

PDB-2n4h:
Solution Structure of the Q343R Mutant of TDP-43 Amyloidogenic Core Region
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN / TDP-43 / Amyloidogenic Core Region / G335D / Q343R

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