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-Structure paper
Title | Structural and Functional Consequences of Three Cancer-Associated Mutations of the Oncogenic Phosphatase SHP2. |
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Journal, issue, pages | Biochemistry, Vol. 55, Page 2269-2277, Year 2016 |
Publish date | Feb 16, 2016 (structure data deposition date) |
![]() | LaRochelle, J.R. / Fodor, M. / Xu, X. / Durzynska, I. / Fan, L. / Stams, T. / Chan, H.M. / LaMarche, M.J. / Chopra, R. / Wang, P. ...LaRochelle, J.R. / Fodor, M. / Xu, X. / Durzynska, I. / Fan, L. / Stams, T. / Chan, H.M. / LaMarche, M.J. / Chopra, R. / Wang, P. / Fortin, P.D. / Acker, M.G. / Blacklow, S.C. |
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Methods | X-ray diffraction |
Resolution | 1.87 - 2.32 Å |
Structure data | ![]() PDB-5i6v: ![]() PDB-5ibm: ![]() PDB-5ibs: |
Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / SHP2 / Cancer-Associated Mutation / Inhibitors / TYROSINE PHOSPHATASE SHP2 S502P / Tyrosine-protein phosphatase non-receptor type 11 / TYROSINE PHOSPHATASE SHP2 |