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Structure paper

TitleModular Organisation of Inducer Recognition and Allostery in the Tetracycline Repressor
Journal, issue, pagesFEBS J., Vol. 283, Page 2102-, Year 2016
Publish dateOct 17, 2015 (structure data deposition date)
AuthorsWerten, S. / Schneider, J. / Palm, G.J. / Hinrichs, W.
External linksFEBS J. / PubMed:27028290
MethodsX-ray diffraction
Resolution1.63 - 1.9 Å
Structure data

PDB-5fkk:
TetR(D) N82A mutant in complex with anhydrotetracycline and magnesium
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-5fkl:
TetR(D) H100A mutant in complex with anhydrotetracycline and magnesium
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-5fkm:
TetR(D) T103A mutant in complex with anhydrotetracycline and magnesium, I4(1)22
Method: X-RAY DIFFRACTION / Resolution: 1.63 Å

PDB-5fkn:
TetR(D) T103A mutant in complex with anhydrotetracycline and magnesium, P4(3)2(1)2
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-5fko:
TetR(D) E147A mutant in complex with anhydrotetracycline and magnesium
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-SO4:
SULFATE ION

ChemComp-CL:
Unknown entry

ChemComp-TDC:
5A,6-ANHYDROTETRACYCLINE

ChemComp-MG:
Unknown entry

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsTRANSCRIPTION / REPRESSOR / ANTIBIOTIC RESISTANCE / TETR

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