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Structure paper

TitleStructural basis for inhibition of the deadenylase activity of human CNOT6L
Journal, issue, pagesFebs Lett., Vol. 590, Page 1270-1279, Year 2016
Publish dateSep 21, 2015 (structure data deposition date)
AuthorsZhang, Q. / Yan, D. / Guo, E. / Ding, B. / Yang, W. / Liu, R. / Yamamoto, T. / Bartlam, M.
External linksFebs Lett. / PubMed:27013054
MethodsX-ray diffraction
Resolution1.8 - 2.07 Å
Structure data

PDB-5dv2:
Crystal structure of human CNOT6L in complex with cytidine-5'-monophosphate
Method: X-RAY DIFFRACTION / Resolution: 2.07 Å

PDB-5dv4:
Crystal structure of human CNOT6L in complex with neomycin
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-C5P:
CYTIDINE-5'-MONOPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-NMY:
NEOMYCIN / antibiotic*YM

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
KeywordsHYDROLASE / nuclease domain / deadenylase / INHIBITOR complex

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