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Structure paper

TitleRoquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40.
Journal, issue, pagesNat Commun, Vol. 7, Page 11032-11032, Year 2016
Publish dateDec 4, 2015 (structure data deposition date)
AuthorsJanowski, R. / Heinz, G.A. / Schlundt, A. / Wommelsdorf, N. / Brenner, S. / Gruber, A.R. / Blank, M. / Buch, T. / Buhmann, R. / Zavolan, M. ...Janowski, R. / Heinz, G.A. / Schlundt, A. / Wommelsdorf, N. / Brenner, S. / Gruber, A.R. / Blank, M. / Buch, T. / Buhmann, R. / Zavolan, M. / Niessing, D. / Heissmeyer, V. / Sattler, M.
External linksNat Commun / PubMed:27010430
MethodsX-ray diffraction
Resolution2.23 - 3 Å
Structure data

PDB-5f5f:
X-ray structure of Roquin ROQ domain in complex with a Selex-derived hexa-loop RNA motif
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-5f5h:
X-ray structure of Roquin ROQ domain in complex with Ox40 hexa-loop RNA motif
Method: X-RAY DIFFRACTION / Resolution: 2.23 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • mus musculus (house mouse)
KeywordsRNA BINDING PROTEIN / ROQ domain / winged-helix domain / SELEX / Ox40 mRNA

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