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TitleBiosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pair.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 113, Page 3797-3802, Year 2016
Publish dateJun 3, 2015 (structure data deposition date)
AuthorsEl Gamal, A. / Agarwal, V. / Diethelm, S. / Rahman, I. / Schorn, M.A. / Sneed, J.M. / Louie, G.V. / Whalen, K.E. / Mincer, T.J. / Noel, J.P. ...El Gamal, A. / Agarwal, V. / Diethelm, S. / Rahman, I. / Schorn, M.A. / Sneed, J.M. / Louie, G.V. / Whalen, K.E. / Mincer, T.J. / Noel, J.P. / Paul, V.J. / Moore, B.S.
External linksProc. Natl. Acad. Sci. USA / PubMed:27001835
MethodsX-ray diffraction
Resolution1.873 - 1.9784 Å
Structure data

PDB-5buk:
Structure of flavin-dependent chlorinase Mpy16
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-5bul:
Structure of flavin-dependent brominase Bmp2 triple mutant Y302S F306V A345W
Method: X-RAY DIFFRACTION / Resolution: 1.9784 Å

PDB-5bva:
Structure of flavin-dependent brominase Bmp2
Method: X-RAY DIFFRACTION / Resolution: 1.873 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • streptomyces sp. cnq-418 (bacteria)
  • streptomyces (bacteria)
KeywordsOXIDOREDUCTASE / flavin-dependent enzyme / HYDROLASE

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