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Structure paper

TitleStructural basis for germline antibody recognition of HIV-1 immunogens.
Journal, issue, pagesElife, Vol. 5, Year 2016
Publish dateDec 8, 2015 (structure data deposition date)
AuthorsScharf, L. / West, A.P. / Sievers, S.A. / Chen, C. / Jiang, S. / Gao, H. / Gray, M.D. / McGuire, A.T. / Scheid, J.F. / Nussenzweig, M.C. ...Scharf, L. / West, A.P. / Sievers, S.A. / Chen, C. / Jiang, S. / Gao, H. / Gray, M.D. / McGuire, A.T. / Scheid, J.F. / Nussenzweig, M.C. / Stamatatos, L. / Bjorkman, P.J.
External linksElife / PubMed:26997349
MethodsX-ray diffraction
Resolution1.9 - 3.39 Å
Structure data

PDB-5f7e:
Crystal structure of germ-line precursor of 3BNC60 Fab
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-5fa2:
Crystal structure of 426c.TM4deltaV1-3 p120
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-5fec:
Crystal structure of 3BNC60 Fab germline precursor in complex with 426c.TM4deltaV1-3 gp120
Method: X-RAY DIFFRACTION / Resolution: 3.17 Å

PDB-5i9q:
Crystal structure of 3BNC55 Fab in complex with 426c.TM4deltaV1-3 gp120
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-5igx:
Crystal structure of NIH45-46 Fab germline precursor in complex with 426c.TM1deltaV1-3 gp120
Method: X-RAY DIFFRACTION / Resolution: 3.39 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-FLC:
CITRATE ANION

ChemComp-SCN:
THIOCYANATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PGE:
TRIETHYLENE GLYCOL

Source
  • homo sapiens (human)
  • human immunodeficiency virus 1
KeywordsIMMUNE SYSTEM / ANTIBODY / HIV-1

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