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Structure paper

TitleA crucial role of Cys218 in configuring an unprecedented auto-inhibition form of MAP2K7
Journal, issue, pagesBiochem. Biophys. Res. Commun., Vol. 473, Page 476-481, Year 2016
Publish dateJan 19, 2016 (structure data deposition date)
AuthorsSogabe, Y. / Hashimoto, T. / Matsumoto, T. / Kirii, Y. / Sawa, M. / Kinoshita, T.
External linksBiochem. Biophys. Res. Commun. / PubMed:26987717
MethodsX-ray diffraction
Resolution2.1 - 3.06 Å
Structure data

PDB-5b2k:
A crucial role of Cys218 in the stabilization of an unprecedented auto-inhibition form of MAP2K7
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

PDB-5b2l:
A crucial role of Cys218 in the stabilization of an unprecedented auto-inhibition form of MAP2K7
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-5b2m:
A crucial role of Cys218 in the stabilization of an unprecedented auto-inhibition form of MAP2K7
Method: X-RAY DIFFRACTION / Resolution: 3.06 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / protein kinase / Apo structure / auto-inhibition form / mutation / AMPPCP

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