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TitleDistinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos
Journal, issue, pagesEmbo J., Vol. 35, Page 974-, Year 2016
Publish dateJan 21, 2016 (structure data deposition date)
AuthorsRaisch, T. / Bhandari, D. / Sabath, K. / Helms, S. / Valkov, E. / Weichenrieder, O. / Izaurralde, E.
External linksEmbo J. / PubMed:26968986
MethodsX-ray diffraction
Resolution2.9 - 3.1 Å
Structure data

PDB-5fu6:
NOT module of the human CCR4-NOT complex (Crystallization mutant)
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-5fu7:
drosophila nanos NBR peptide bound to the NOT module of the human CCR4-NOT complex
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Source
  • homo sapiens (human)
  • drosophila melanogaster (fruit fly)
KeywordsGENE REGULATION / DEADENYLATION / MRNA DECAY / CCR4-NOT / TRANSCRIPTION / TRANSLATIONAL REPRESSION

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