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| Title | Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors. |
|---|---|
| Journal, issue, pages | Nat. Struct. Mol. Biol., Vol. 23, Page 293-299, Year 2016 |
| Publish date | Apr 29, 2015 (structure data deposition date) |
Authors | Yin, J. / Babaoglu, K. / Brautigam, C.A. / Clark, L. / Shao, Z. / Scheuermann, T.H. / Harrell, C.M. / Gotter, A.L. / Roecker, A.J. / Winrow, C.J. ...Yin, J. / Babaoglu, K. / Brautigam, C.A. / Clark, L. / Shao, Z. / Scheuermann, T.H. / Harrell, C.M. / Gotter, A.L. / Roecker, A.J. / Winrow, C.J. / Renger, J.J. / Coleman, P.J. / Rosenbaum, D.M. |
External links | Nat. Struct. Mol. Biol. / PubMed:26950369 |
| Methods | X-ray diffraction |
| Resolution | 2.751 - 2.832 Å |
| Structure data | ![]() PDB-4zj8: ![]() PDB-4zjc: |
| Chemicals | ![]() ChemComp-SUV: ![]() ChemComp-OLA: ![]() ChemComp-HOH: ![]() ChemComp-4OT: |
| Source |
|
Keywords | SIGNALING PROTEIN / Orexin / suvorexant / SB674042 / SB-674042 / MEMBRANE PROTEIN-Transferase complex |
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homo sapiens (human)
pyrococcus abyssi (strain ge5 / orsay) (archaea)
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