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Structure paper

TitleX-ray Crystallographic Structure of Oligomers Formed by a Toxic beta-Hairpin Derived from alpha-Synuclein: Trimers and Higher-Order Oligomers.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 138, Page 4458-4467, Year 2016
Publish dateNov 30, 2015 (structure data deposition date)
AuthorsSalveson, P.J. / Spencer, R.K. / Nowick, J.S.
External linksJ. Am. Chem. Soc. / PubMed:26926877
MethodsX-ray diffraction
Resolution1.971 - 2.161 Å
Structure data

PDB-5f1t:
Crystal structure of a macrocyclic peptide containing fragments from alpha-synuclein 36-55.
Method: X-RAY DIFFRACTION / Resolution: 1.971 Å

PDB-5f1w:
Crystal structure of the enantiomer of a macrocyclic peptide containing fragments from alpha synuclein 36-55
Method: X-RAY DIFFRACTION / Resolution: 2.161 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-SO4:
SULFATE ION

ChemComp-MRD:
(4R)-2-METHYLPENTANE-2,4-DIOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • synthetic construct (others)
KeywordsIMMUNE SYSTEM / beta-Hairpins

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