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TitleStructure, Aggregation, and Activity of a Covalent Insulin Dimer Formed During Storage of Neutral Formulation of Human Insulin.
Journal, issue, pagesJ. Pharm. Sci., Vol. 105, Page 1376-1386, Year 2016
Publish dateJun 3, 2015 (structure data deposition date)
AuthorsHjorth, C.F. / Norrman, M. / Wahlund, P.O. / Benie, A.J. / Petersen, B.O. / Jessen, C.M. / Pedersen, T.A. / Vestergaard, K. / Steensgaard, D.B. / Pedersen, J.S. ...Hjorth, C.F. / Norrman, M. / Wahlund, P.O. / Benie, A.J. / Petersen, B.O. / Jessen, C.M. / Pedersen, T.A. / Vestergaard, K. / Steensgaard, D.B. / Pedersen, J.S. / Naver, H. / Hubalek, F. / Poulsen, C. / Otzen, D.
External linksJ. Pharm. Sci. / PubMed:26921119
MethodsX-ray diffraction
Resolution1.77 Å
Structure data

PDB-5bts:
Structural and biophysical characterization of a covalent insulin dimer formed during storage of neutral formulation of human insulin
Method: X-RAY DIFFRACTION / Resolution: 1.77 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHORMONE / Insulin / HMWP

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