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Structure paper

TitleA Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
Journal, issue, pagesJ. Biol. Chem., Vol. 291, Page 8951-8959, Year 2016
Publish dateNov 18, 2015 (structure data deposition date)
AuthorsBianchi, V. / Bulek, A. / Fuller, A. / Lloyd, A. / Attaf, M. / Rizkallah, P.J. / Dolton, G. / Sewell, A.K. / Cole, D.K.
External linksJ. Biol. Chem. / PubMed:26917722
MethodsX-ray diffraction
Resolution1.54 - 2.12 Å
Structure data

PDB-5eu3:
HLA Class I antigen
Method: X-RAY DIFFRACTION / Resolution: 1.97 Å

PDB-5eu4:
HLA Class I antigen
Method: X-RAY DIFFRACTION / Resolution: 2.12 Å

PDB-5eu5:
HLA Class I antigen
Method: X-RAY DIFFRACTION / Resolution: 1.54 Å

PDB-5eu6:
HLA Class I antigen
Method: X-RAY DIFFRACTION / Resolution: 2.02 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsIMMUNE SYSTEM / IMMUNO / HLA-A02 / 1E6-TCR / Cross-reactivity

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