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TitleInterplay of histidine residues of the Alzheimer's disease A beta peptide governs its Zn-induced oligomerization.
Journal, issue, pagesSci Rep, Vol. 6, Page 21734-21734, Year 2016
Publish dateNov 6, 2013 (structure data deposition date)
AuthorsIstrate, A.N. / Kozin, S.A. / Zhokhov, S.S. / Mantsyzov, A.B. / Kechko, O.I. / Pastore, A. / Makarov, A.A. / Polshakov, V.I.
External linksSci Rep / PubMed:26898943
MethodsNMR (solution)
Structure data

PDB-2mgt:
Zinc induced dimer of the metal binding domain 1-16 of human amyloid beta-peptide with Alzheimer's disease pathogenic English mutation H6R
Method: SOLUTION NMR

Chemicals

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsPROTEIN FIBRIL / METAL BINDING PROTEIN / Alzheimer's disease / Human amyloid -peptide / Zinc binding

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