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Structure paper

TitleThe cap-binding site of influenza virus protein PB2 as a drug target.
Journal, issue, pagesActa Crystallogr D Struct Biol, Vol. 72, Page 245-253, Year 2016
Publish dateOct 26, 2015 (structure data deposition date)
AuthorsSeverin, C. / Rocha de Moura, T. / Liu, Y. / Li, K. / Zheng, X. / Luo, M.
External linksActa Crystallogr D Struct Biol / PubMed:26894672
MethodsX-ray diffraction
Resolution1.4 - 2.3 Å
Structure data

PDB-5eg7:
The cap binding site of influenza virus protein PB2 as a drug target
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-5eg8:
The cap binding site of influenza virus protein PB2 as a drug target
Method: X-RAY DIFFRACTION / Resolution: 1.54 Å

PDB-5eg9:
The cap binding site of influenza virus protein PB2 as a drug target
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-MGT:
7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-SCN:
THIOCYANATE ION

Source
  • influenza a virus
  • influenza a virus (a/swine/quebec/1257777/2010(h3n2))
KeywordsVIRAL PROTEIN / PB2 cap / PB2 cap native

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