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Structure paper

TitlePathogenic C9ORF72 Antisense Repeat RNA Forms a Double Helix with Tandem C:C Mismatches.
Journal, issue, pagesBiochemistry, Vol. 55, Page 1283-1286, Year 2016
Publish dateNov 20, 2015 (structure data deposition date)
AuthorsDodd, D.W. / Tomchick, D.R. / Corey, D.R. / Gagnon, K.T.
External linksBiochemistry / PubMed:26878348
MethodsX-ray diffraction
Resolution1.47 - 1.75 Å
Structure data

PDB-5ew4:
Crystal structure of C9ORF72 Antisense CCCCGG repeat RNA associated with Lou Gehrig's disease and frontotemporal dementia, crystallized with Sr2+
Method: X-RAY DIFFRACTION / Resolution: 1.47 Å

PDB-5ew7:
Crystal structure of C9ORF72 Antisense CCCCGG repeat RNA associated with Lou Gehrig's disease and frontotemporal dementia, crystallized with Ba2+
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-K:
Unknown entry

ChemComp-SR:
STRONTIUM ION

ChemComp-MG:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-BA:
Unknown entry

Source
  • homo sapiens (human)
KeywordsRNA / REPEAT EXPANSION DISORDER / GENETIC DISEASE

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