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TitleCrystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase at 1.0 angstrom resolution - a potential target for anti-tuberculosis drug discovery.
Journal, issue, pagesFebs J., Vol. 283, Page 1184-1196, Year 2016
Publish dateMar 13, 2015 (structure data deposition date)
AuthorsLv, Y. / Kandale, A. / Wun, S.J. / McGeary, R.P. / Williams, S.J. / Kobe, B. / Sieber, V. / Schembri, M.A. / Schenk, G. / Guddat, L.W.
External linksFebs J. / PubMed:26876563
MethodsX-ray diffraction
Resolution1.001 Å
Structure data

PDB-4ypo:
Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase in complex with Mg2+
Method: X-RAY DIFFRACTION / Resolution: 1.001 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsOXIDOREDUCTASE / ilvC / Branch chain amino acids / Knotted protein / Rossmann fold

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