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TitleUnique Flap Conformation in an HIV-1 Protease with High-Level Darunavir Resistance
Journal, issue, pagesFront Microbiol, Vol. 7, Page 61-61, Year 2016
Publish dateNov 30, 2015 (structure data deposition date)
AuthorsNakashima, M. / Ode, H. / Suzuki, K. / Fujino, M. / Maejima, M. / Kimura, Y. / Masaoka, T. / Hattori, J. / Matsuda, M. / Hachiya, A. ...Nakashima, M. / Ode, H. / Suzuki, K. / Fujino, M. / Maejima, M. / Kimura, Y. / Masaoka, T. / Hattori, J. / Matsuda, M. / Hachiya, A. / Yokomaku, Y. / Suzuki, A. / Watanabe, N. / Sugiura, W. / Iwatani, Y.
External linksFront Microbiol / PubMed:26870021
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-5b18:
Crystal Structure of a Darunavir Resistant HIV-1 Protease
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus 1
KeywordsHYDROLASE / HIV-1 protease / drug resistance / darunavir / flap

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