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Structure paper

TitleAncestral Protein Reconstruction Yields Insights into Adaptive Evolution of Binding Specificity in Solute-Binding Proteins.
Journal, issue, pagesCell Chem Biol, Vol. 23, Page 236-245, Year 2016
Publish dateMay 18, 2015 (structure data deposition date)
AuthorsClifton, B.E. / Jackson, C.J.
External linksCell Chem Biol / PubMed:26853627
MethodsX-ray diffraction
Resolution1.43 - 1.52 Å
Structure data

PDB-4zv1:
An ancestral arginine-binding protein bound to arginine
Method: X-RAY DIFFRACTION / Resolution: 1.52 Å

PDB-4zv2:
An ancestral arginine-binding protein bound to glutamine
Method: X-RAY DIFFRACTION / Resolution: 1.43 Å

Chemicals

ChemComp-ARG:
ARGININE

ChemComp-HOH:
WATER

ChemComp-GLN:
GLUTAMINE

Source
  • synthetic construct (others)
KeywordsSOLUTE-BINDING PROTEIN / periplasmic binding protein / solute binding protein / transport / amino acid

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