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-Structure paper
Title | TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 113, Page E884-E893, Year 2016 |
Publish date | Mar 1, 2016 (structure data deposition date) |
![]() | Wang, Y. / Su, L. / Morin, M.D. / Jones, B.T. / Whitby, L.R. / Surakattula, M.M. / Huang, H. / Shi, H. / Choi, J.H. / Wang, K.W. ...Wang, Y. / Su, L. / Morin, M.D. / Jones, B.T. / Whitby, L.R. / Surakattula, M.M. / Huang, H. / Shi, H. / Choi, J.H. / Wang, K.W. / Moresco, E.M. / Berger, M. / Zhan, X. / Zhang, H. / Boger, D.L. / Beutler, B. |
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Methods | X-ray diffraction |
Resolution | 2.57 - 2.91 Å |
Structure data | ![]() PDB-5ijb: ![]() PDB-5ijc: ![]() PDB-5ijd: |
Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-V2A: ![]() ChemComp-HOH: ![]() ChemComp-LP4: ![]() ChemComp-LP5: ![]() ChemComp-DAO: ![]() ChemComp-MYR: |
Source |
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![]() | IMMUNE SYSTEM / leucine-rich repeats / Immune response / protein complex / small molecule agonist / natural agonist |