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TitleToxoplasma gondii peptide ligands open the gate of the HLA class I binding groove.
Journal, issue, pagesElife, Vol. 5, Year 2016
Publish dateAug 19, 2015 (structure data deposition date)
AuthorsMcMurtrey, C. / Trolle, T. / Sansom, T. / Remesh, S.G. / Kaever, T. / Bardet, W. / Jackson, K. / McLeod, R. / Sette, A. / Nielsen, M. ...McMurtrey, C. / Trolle, T. / Sansom, T. / Remesh, S.G. / Kaever, T. / Bardet, W. / Jackson, K. / McLeod, R. / Sette, A. / Nielsen, M. / Zajonc, D.M. / Blader, I.J. / Peters, B. / Hildebrand, W.
External linksElife / PubMed:26824387
MethodsX-ray diffraction
Resolution1.5 - 1.87 Å
Structure data

PDB-5d9s:
Structure of HLA-A2:01 with the 11-mer peptide F11V
Method: X-RAY DIFFRACTION / Resolution: 1.87 Å

PDB-5ddh:
Structure of HLA-A2:01 with the 12-mer peptide F12K
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • toxoplasma gondii (eukaryote)
KeywordsIMMUNE SYSTEM / Peptide complex / MHC / Peptide-protein complex

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