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TitleTCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL.
Journal, issue, pagesSci Rep, Vol. 6, Page 19725-19725, Year 2016
Publish dateApr 12, 2015 (structure data deposition date)
AuthorsThebault, S. / Agez, M. / Chi, X. / Stojko, J. / Cura, V. / Telerman, S.B. / Maillet, L. / Gautier, F. / Billas-Massobrio, I. / Birck, C. ...Thebault, S. / Agez, M. / Chi, X. / Stojko, J. / Cura, V. / Telerman, S.B. / Maillet, L. / Gautier, F. / Billas-Massobrio, I. / Birck, C. / Troffer-Charlier, N. / Karafin, T. / Honore, J. / Senff-Ribeiro, A. / Montessuit, S. / Johnson, C.M. / Juin, P. / Cianferani, S. / Martinou, J.C. / Andrews, D.W. / Amson, R. / Telerman, A. / Cavarelli, J.
External linksSci Rep / PubMed:26813996
MethodsX-ray diffraction
Resolution2.099 Å
Structure data

PDB-4z9v:
TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL
Method: X-RAY DIFFRACTION / Resolution: 2.099 Å

Chemicals

ChemComp-BCT:
BICARBONATE ION / pH buffer*YM

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsAPOPTOSIS / TCTP / apoptose / BH3

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