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-Structure paper
Title | Discovery of the Aryl-phospho-indole IDX899, a Highly Potent Anti-HIV Non-nucleoside Reverse Transcriptase Inhibitor. |
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Journal, issue, pages | J. Med. Chem., Vol. 59, Page 1891-1898, Year 2016 |
Publish date | Dec 16, 2015 (structure data deposition date) |
![]() | Dousson, C. / Alexandre, F.R. / Amador, A. / Bonaric, S. / Bot, S. / Caillet, C. / Convard, T. / da Costa, D. / Lioure, M.P. / Roland, A. ...Dousson, C. / Alexandre, F.R. / Amador, A. / Bonaric, S. / Bot, S. / Caillet, C. / Convard, T. / da Costa, D. / Lioure, M.P. / Roland, A. / Rosinovsky, E. / Maldonado, S. / Parsy, C. / Trochet, C. / Storer, R. / Stewart, A. / Wang, J. / Mayes, B.A. / Musiu, C. / Poddesu, B. / Vargiu, L. / Liuzzi, M. / Moussa, A. / Jakubik, J. / Hubbard, L. / Seifer, M. / Standring, D. |
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Methods | X-ray diffraction |
Resolution | 3.1 Å |
Structure data | ![]() PDB-5fdl: |
Chemicals | ![]() ChemComp-5DV: |
Source |
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![]() | HYDROLASE / HIV-1 Reverse Transcriptase / Phosphoindole / NNRTI / Mutation |