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Structure paper

TitleStructure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome.
Journal, issue, pagesNucleic Acids Res., Vol. 44, Page 2429-2438, Year 2016
Publish dateDec 9, 2015 (structure data deposition date)
AuthorsSeefeldt, A.C. / Graf, M. / Perebaskine, N. / Nguyen, F. / Arenz, S. / Mardirossian, M. / Scocchi, M. / Wilson, D.N. / Innis, C.A.
External linksNucleic Acids Res. / PubMed:26792896
MethodsX-ray diffraction
Resolution2.8 - 2.9 Å
Structure data

PDB-5f8k:
Crystal structure of the Bac7(1-16) antimicrobial peptide bound to the Thermus thermophilus 70S ribosome
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-5fdu:
Crystal structure of the Metalnikowin I antimicrobial peptide bound to the Thermus thermophilus 70S ribosome
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-5fdv:
Crystal structure of the Pyrrhocoricin antimicrobial peptide bound to the Thermus thermophilus 70S ribosome
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-K:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-AMP:
ADENOSINE MONOPHOSPHATE / AMP*YM

Source
  • escherichia coli (E. coli)
  • thermus thermophilus hb8 (bacteria)
  • synthetic construct (others)
  • bos taurus (domestic cattle)
  • escherichia coli (strain k12) (bacteria)
  • thermus thermophilus (strain hb8 / atcc 27634 / dsm 579) (bacteria)
  • palomena prasina (green shield bug)
  • escherichia coli k-12 (bacteria)
  • pyrrhocoris apterus (insect)
KeywordsRIBOSOME / bacterial ribosome / proline-rich antimicrobial peptide / antibiotics / protein biosynthesis

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