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TitleCrystal structure of the FK506 binding domain of human FKBP25 in complex with FK506.
Journal, issue, pagesProtein Sci., Vol. 25, Page 905-910, Year 2016
Publish dateAug 13, 2015 (structure data deposition date)
AuthorsPrakash, A. / Rajan, S. / Yoon, H.S.
External linksProtein Sci. / PubMed:26749369
MethodsX-ray diffraction
Resolution1.83 Å
Structure data

PDB-5d75:
Crystal structure of Human FKBD25 in complex with FK506
Method: X-RAY DIFFRACTION / Resolution: 1.83 Å

Chemicals

ChemComp-FK5:
8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN / medication*YM

ChemComp-JEF:
O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500)

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsISOMERASE/INHIBITOR / FK506 / FKBP25 / FKBP3 / Immunophilin / Inhibitor / ISOMERASE-INHIBITOR complex

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