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Structure paper

TitleTargeted Redox Inhibition of Protein Phosphatase 1 by Nox4 Regulates Eif2Alpha-Mediated Stress Signaling.
Journal, issue, pagesEmbo J., Vol. 35, Page 319-, Year 2016
Publish dateJul 17, 2014 (structure data deposition date)
AuthorsSantos, C.X. / Hafstad, A.D. / Beretta, M. / Zhang, M. / Molenaar, C. / Kopec, J. / Fotinou, D. / Murray, T.V. / Cobb, A.M. / Martin, D. ...Santos, C.X. / Hafstad, A.D. / Beretta, M. / Zhang, M. / Molenaar, C. / Kopec, J. / Fotinou, D. / Murray, T.V. / Cobb, A.M. / Martin, D. / Zeh Silva, M. / Anilkumar, N. / Schroder, K. / Shanahan, C.M. / Brewer, A.C. / Brandes, R.P. / Blanc, E. / Parsons, M. / Belousov, V. / Cammack, R. / Hider, R.C. / Steiner, R.A. / Shah, A.M.
External linksEmbo J. / PubMed:26742780
MethodsX-ray diffraction
Resolution1.96 - 2.19 Å
Structure data

PDB-4ut2:
X-ray structure of the human PP1 gamma catalytic subunit treated with ascorbate
Method: X-RAY DIFFRACTION / Resolution: 1.96 Å

PDB-4ut3:
X-ray structure of the human PP1 gamma catalytic subunit treated with hydrogen peroxide
Method: X-RAY DIFFRACTION / Resolution: 2.19 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / METAL CENTER / METALLOPROTEIN / ENZYME ACTIVATION / PHOSPHOPROTEIN PHOSPHATASES / PROTEIN PHOSPHATASE 1

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