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-Structure paper
Title | The crystal structure of a 2',4'-BNA(NC)[N-Me]-modified antisense gapmer in complex with the target RNA. |
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Journal, issue, pages | Chem. Commun. (Camb. ), Vol. 52, Page 2354-2357, Year 2016 |
Publish date | Jul 29, 2014 (structure data deposition date) |
Authors | Kondo, J. / Nomura, Y. / Kitahara, Y. / Obika, S. / Torigoe, H. |
External links | Chem. Commun. (Camb. ) / PubMed:26731288 |
Methods | X-ray diffraction |
Resolution | 1.5 - 1.9 Å |
Structure data | PDB-4u6k: PDB-4u6l: PDB-4u6m: |
Chemicals | ChemComp-NCO: ChemComp-HOH: ChemComp-SR: |
Source |
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Keywords | DNA/RNA / DNA/RNA duplex / antisense / Bridged Nucleic Acid / DNA-RNA complex / DNA/RNA hybrid duplex |