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TitleStructural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site.
Journal, issue, pagesCell Rep, Vol. 14, Page 43-54, Year 2016
Publish dateDec 6, 2015 (structure data deposition date)
AuthorsBradley, T. / Fera, D. / Bhiman, J. / Eslamizar, L. / Lu, X. / Anasti, K. / Zhang, R. / Sutherland, L.L. / Scearce, R.M. / Bowman, C.M. ...Bradley, T. / Fera, D. / Bhiman, J. / Eslamizar, L. / Lu, X. / Anasti, K. / Zhang, R. / Sutherland, L.L. / Scearce, R.M. / Bowman, C.M. / Stolarchuk, C. / Lloyd, K.E. / Parks, R. / Eaton, A. / Foulger, A. / Nie, X. / Karim, S.S. / Barnett, S. / Kelsoe, G. / Kepler, T.B. / Alam, S.M. / Montefiori, D.C. / Moody, M.A. / Liao, H.X. / Morris, L. / Santra, S. / Harrison, S.C. / Haynes, B.F.
External linksCell Rep / PubMed:26725118
MethodsX-ray diffraction
Resolution2.32 - 6.63 Å
Structure data

PDB-5f6h:
Crystal Structure of Tier 2 Neutralizing Antibody DH427 from a Rhesus Macaque
Method: X-RAY DIFFRACTION / Resolution: 2.66 Å

PDB-5f6i:
Crystal Structure of Tier 2 Neutralizing Antibody DH428 from a Rhesus Macaque
Method: X-RAY DIFFRACTION / Resolution: 2.32 Å

PDB-5f6j:
Crystal Structure of Tier 2 Neutralizing Antibody DH427 from a Rhesus Macaque in Complex with HIV-1 gp120 Core
Method: X-RAY DIFFRACTION / Resolution: 6.63 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • macaca mulatta (Rhesus monkey)
  • human immunodeficiency virus 1
KeywordsIMMUNE SYSTEM / FAB FRAGMENT / HIV-1 / ANTIBODY / Viral Protein/Immue System / Viral Protein-Immue System complex

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