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TitleStructural and Mechanistic Insights Into the Regulation of the Fundamental Rho-Regulator Rhogdi Alpha by Lysine Acetylation.
Journal, issue, pagesJ. Biol. Chem., Vol. 291, Page 5484-, Year 2016
Publish dateDec 15, 2015 (structure data deposition date)
AuthorsKuhlmann, N. / Wroblowski, S. / Knyphausen, P. / De Boor, S. / Brenig, J. / Zienert, A.Y. / Meyer-Teschendorf, K. / Praefcke, G.J.K. / Nolte, H. / Kruger, M. ...Kuhlmann, N. / Wroblowski, S. / Knyphausen, P. / De Boor, S. / Brenig, J. / Zienert, A.Y. / Meyer-Teschendorf, K. / Praefcke, G.J.K. / Nolte, H. / Kruger, M. / Schacherl, M. / Baumann, U. / James, L.C. / Chin, J.W. / Lammers, M.
External linksJ. Biol. Chem. / PubMed:26719334
MethodsX-ray diffraction
Resolution3.35 Å
Structure data

PDB-5fr2:
Farnesylated RhoA-GDP in complex with RhoGDI-alpha, lysine acetylated at K178
Method: X-RAY DIFFRACTION / Resolution: 3.35 Å

Chemicals

ChemComp-FAR:
FARNESYL

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-BGC:
beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • bos taurus (domestic cattle)
KeywordsSIGNALING PROTEIN / LYSINE-ACETYLATION / RHOA / RAS-SUPERFAMILY / RHOGDI / CYTOSKELETON / GDP

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