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Structure paper

TitleMutational Constraints on Local Unfolding Inhibit the Rheological Adaptation of von Willebrand Factor.
Journal, issue, pagesJ. Biol. Chem., Vol. 291, Page 3848-3859, Year 2016
Publish dateJun 4, 2015 (structure data deposition date)
AuthorsTischer, A. / Campbell, J.C. / Machha, V.R. / Moon-Tasson, L. / Benson, L.M. / Sankaran, B. / Kim, C. / Auton, M.
External linksJ. Biol. Chem. / PubMed:26677223
MethodsX-ray diffraction
Resolution1.59 Å
Structure data

PDB-5bv8:
G1324S mutation in von Willebrand Factor A1 domain
Method: X-RAY DIFFRACTION / Resolution: 1.59 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsBLOOD CLOTTING / von Willebrand Factor / Platelet adhesion / VWFA

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