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Structure paper

TitleBinding of DNA-Intercalating Agents to Oxidized and Reduced Quinone Reductase 2.
Journal, issue, pagesBiochemistry, Vol. 54, Page 7438-7448, Year 2015
Publish dateMay 18, 2015 (structure data deposition date)
AuthorsLeung, K.K. / Shilton, B.H.
External linksBiochemistry / PubMed:26636353
MethodsX-ray diffraction
Resolution1.866 - 1.973 Å
Structure data

PDB-4zvk:
Reduced quinone reductase 2 in complex with ethidium
Method: X-RAY DIFFRACTION / Resolution: 1.867 Å

PDB-4zvl:
Oxidized quinone reductase 2 in complex with acridine orange
Method: X-RAY DIFFRACTION / Resolution: 1.899 Å

PDB-4zvm:
Oxidized quinone reductase 2 in complex with doxorubicin
Method: X-RAY DIFFRACTION / Resolution: 1.973 Å

PDB-4zvn:
Reduced quinone reductase 2 in complex with acridine orange
Method: X-RAY DIFFRACTION / Resolution: 1.866 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-ET:
ETHIDIUM

ChemComp-HOH:
WATER

ChemComp-AO:
ACRIDINE ORANGE

ChemComp-DM2:
DOXORUBICIN / medication, chemotherapy*YM

Source
  • homo sapiens (human)
KeywordsOxidoreductase/oxidoreductase Inhibitor / quinone reductase 2 / ethidium bromide / Oxidoreductase-Inhibitor complex / Oxidoreductase-oxidoreductase Inhibitor complex / Oxidoreductase/Inhibitor / acridine orange / doxorubicin

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