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TitleStructure of full-length human anti-PD1 therapeutic IgG4 antibody pembrolizumab.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 22, Page 953-958, Year 2015
Publish dateSep 2, 2015 (structure data deposition date)
AuthorsScapin, G. / Yang, X. / Prosise, W.W. / McCoy, M. / Reichert, P. / Johnston, J.M. / Kashi, R.S. / Strickland, C.
External linksNat. Struct. Mol. Biol. / PubMed:26595420
MethodsX-ray diffraction
Resolution2.28 Å
Structure data

PDB-5dk3:
Crystal Structure of Pembrolizumab, a full length IgG4 antibody
Method: X-RAY DIFFRACTION / Resolution: 2.28 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Cancer / Antibody / subclasses / IgG4 / melanoma

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