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TitleStructural insights into the loss of penicillinase and the gain of ceftazidimase activities by OXA-145 beta-lactamase in Pseudomonas aeruginosa.
Journal, issue, pagesJ. Antimicrob. Chemother., Vol. 71, Page 395-402, Year 2016
Publish dateMar 2, 2015 (structure data deposition date)
AuthorsMeziane-Cherif, D. / Bonnet, R. / Haouz, A. / Courvalin, P.
External linksJ. Antimicrob. Chemother. / PubMed:26568564
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-4yin:
Crystal structure of the extended-spectrum beta-lactamase OXA-145
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-FLC:
CITRATE ANION

ChemComp-HOH:
WATER

Source
  • pseudomonas aeruginosa (bacteria)
KeywordsHYDROLASE / antibiotic resistance / extended-spectrum beta-lactamase / class D / oxacillinase

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