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TitleHumanized Affinity-matured Monoclonal Antibody 8H9 Has Potent Antitumor Activity and Binds to FG Loop of Tumor Antigen B7-H3.
Journal, issue, pagesJ. Biol. Chem., Vol. 290, Page 30018-30029, Year 2015
Publish dateJul 16, 2015 (structure data deposition date)
AuthorsAhmed, M. / Cheng, M. / Zhao, Q. / Goldgur, Y. / Cheal, S.M. / Guo, H.F. / Larson, S.M. / Cheung, N.K.
External linksJ. Biol. Chem. / PubMed:26487718
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-5cma:
Anti-B7-H3 monoclonal antibody ch8H9 Fab fragment
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / B7-H3 8H9 monoclonal antibody

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