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Structure paper

TitleDiscovery and characterization of an antibody directed against exosite I of thrombin.
Journal, issue, pagesJ. Thromb. Haemost., Vol. 14, Page 137-142, Year 2016
Publish dateOct 14, 2015 (structure data deposition date)
AuthorsBaglin, T.P. / Langdown, J. / Frasson, R. / Huntington, J.A.
External linksJ. Thromb. Haemost. / PubMed:26469093
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-5e8e:
Crystal structure of thrombin bound to an exosite 1-specific IgA Fab
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-PO4:
PHOSPHATE ION

ChemComp-CIT:
CITRIC ACID

ChemComp-NA:
Unknown entry

ChemComp-0G6:
D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM/HYDROLASE / IMMUNE SYSTEM-HYDROLASE COMPLEX / IMMUNE SYSTEM / INHIBITOR

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