EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Design of composite inhibitors targeting glutamate carboxypeptidase II: the importance of effector functionalities.
ジャーナル・号・ページ	Febs J., Vol. 283, Page 130-143, Year 2016
掲載日	2014年3月11日 (構造データの登録日)
著者	Novakova, Z. / Cerny, J. / Choy, C.J. / Nedrow, J.R. / Choi, J.K. / Lubkowski, J. / Berkman, C.E. / Barinka, C.
リンク	Febs J. / PubMed:26460595
手法	X線回折
解像度	1.65 - 1.93 Å
構造データ	PDB-4p44: X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a phosphoramidate inhibitor JRB-4-81 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-4p45: X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a phosphoramidate inhibitor JRB-4-73 手法: X-RAY DIFFRACTION / 解像度: 1.87 Å PDB-4p4b: X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a phosphoramidate inhibitor CTT54 手法: X-RAY DIFFRACTION / 解像度: 1.93 Å PDB-4p4d: X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a phosphoramidate inhibitor MP1C 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å PDB-4p4e: X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a phosphoramidate inhibitor MP1D 手法: X-RAY DIFFRACTION / 解像度: 1.67 Å PDB-4p4f: X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a phosphoramidate inhibitor NC-2-40 手法: X-RAY DIFFRACTION / 解像度: 1.86 Å PDB-4p4i: X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a phosphoramidate inhibitor T33 手法: X-RAY DIFFRACTION / 解像度: 1.87 Å PDB-4p4j: X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a phosphoramidate inhibitor T33D 手法: X-RAY DIFFRACTION / 解像度: 1.66 Å
化合物	ChemComp-NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose / N-アセチル-β-D-グルコサミン ChemComp-ZN: Unknown entry ChemComp-CA: Unknown entry / カルシウムジカチオン ChemComp-CL: Unknown entry / クロリド ChemComp-2F7: N-(4-fluorobenzoyl)-L-alloisoleucyl-O-[(S)-{[(1S)-1,3-dicarboxypropyl]amino}(hydroxy)phosphoryl]-L-serine ChemComp-HOH: WATER ChemComp-2F9: N-(4-fluorobenzoyl)-L-valyl-O-[(S)-{[(1S)-1,3-dicarboxypropyl]amino}(hydroxy)phosphoryl]-L-serine ChemComp-2G2: L-gamma-glutamyl-O-[(S)-{[(1S)-1,3-dicarboxypropyl]amino}(hydroxy)phosphoryl]-L-serine ChemComp-2GR: N-[(S)-[2-(benzoylamino)ethoxy](hydroxy)phosphoryl]-L-glutamic acid / N-[[2-(ベンゾイルアミノ)エトキシ](ヒドロキシ)ホスフィニル]-L-グルタミン酸 ChemComp-2G4: N-[(S)-hydroxy(4-phenylbutoxy)phosphoryl]-L-glutamic acid ChemComp-2GB: N-[(S)-(biphenyl-4-ylmethoxy)(hydroxy)phosphoryl]-L-glutamic acid ChemComp-2G5: N-[(S)-[(2S)-2-(benzoylamino)-2-carboxyethoxy](hydroxy)phosphoryl]-L-glutamic acid / N-[[(2S)-2-(ベンゾイルアミノ)-3-ヒドロキシ-3-オキソプロポキシ](ヒドロキシ)ホスフィニル]-L-グ(以下略) ChemComp-2H9: N-[(S)-[(2R)-2-(benzoylamino)-2-carboxyethoxy](hydroxy)phosphoryl]-L-glutamic acid / N-[[(2R)-2-(ベンゾイルアミノ)-3-ヒドロキシ-3-オキソプロポキシ](ヒドロキシ)ホスフィニル]-L-グ(以下略)
由来	homo sapiens (ヒト)
キーワード	HYDROLASE / prostate-specific membrane antigen / NAALADase / phosphoramidate / glutamate carboxypeptidase II (GCPII) / glutamate carboxypeptidase II (GCPII); NAALADase; prostate-specific membrane antigen; phosphoramidate