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TitleComplete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 71, Page 2099-2108, Year 2015
Publish dateJun 24, 2015 (structure data deposition date)
AuthorsKong, L. / Torrents de la Pena, A. / Deller, M.C. / Garces, F. / Sliepen, K. / Hua, Y. / Stanfield, R.L. / Sanders, R.W. / Wilson, I.A.
External linksActa Crystallogr. ,Sect. D / PubMed:26457433
MethodsX-ray diffraction
Resolution4.6019 Å
Structure data

PDB-5c7k:
Crystal structure BG505 SOSIP gp140 HIV-1 Env trimer bound to broadly neutralizing antibodies PGT128 and 8ANC195
Method: X-RAY DIFFRACTION / Resolution: 4.6019 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
  • human immunodeficiency virus 1
KeywordsIMMUNE SYSTEM / HIV-1 / SOSIP / PGT128 / 8ANC195

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