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TitleMechanism of MenE Inhibition by Acyl-Adenylate Analogues and Discovery of Novel Antibacterial Agents.
Journal, issue, pagesBiochemistry, Vol. 54, Page 6514-6524, Year 2015
Publish dateJun 19, 2015 (structure data deposition date)
AuthorsMatarlo, J.S. / Evans, C.E. / Sharma, I. / Lavaud, L.J. / Ngo, S.C. / Shek, R. / Rajashankar, K.R. / French, J.B. / Tan, D.S. / Tonge, P.J.
External linksBiochemistry / PubMed:26394156
MethodsX-ray diffraction
Resolution2.401 Å
Structure data

PDB-5c5h:
R195K E. coli MenE with bound OSB-AMS
Method: X-RAY DIFFRACTION / Resolution: 2.401 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-4YB:
5'-O-{[4-(2-carboxyphenyl)-4-oxobutanoyl]sulfamoyl}adenosine

ChemComp-HOH:
WATER

Source
  • escherichia coli (strain k12) (bacteria)
KeywordsLIGASE

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