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Structure paper

TitleArchitecture of the eIF2B regulatory subcomplex and its implications for the regulation of guanine nucleotide exchange on eIF2.
Journal, issue, pagesNucleic Acids Res., Vol. 43, Page 9994-10014, Year 2015
Publish dateApr 20, 2015 (structure data deposition date)
AuthorsKuhle, B. / Eulig, N.K. / Ficner, R.
External linksNucleic Acids Res. / PubMed:26384431
MethodsX-ray diffraction
Resolution2.55 - 3 Å
Structure data

PDB-4zem:
Crystal structure of eIF2B beta from Chaetomium thermophilum
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

PDB-4zeo:
Crystal structure of eIF2B delta from Chaetomium thermophilum
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

PDB-5dbo:
Crystal structure of the tetrameric eIF2B-beta2-delta2 complex from C. thermophilum
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • chaetomium thermophilum (fungus)
KeywordsTRANSLATION / eIF2B / eIF2 / guanine nucleotide exchange factor / GEF / regulatory subcomplex / regulatory subunit / translation initiation / translational regulation / exchange factor / complex

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