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TitleThe Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism.
Journal, issue, pagesStructure, Vol. 23, Page 1989-2000, Year 2015
Publish dateNov 16, 2014 (structure data deposition date)
AuthorsGuez-Haddad, J. / Sporny, M. / Sasson, Y. / Gevorkyan-Airapetov, L. / Lahav-Mankovski, N. / Margulies, D. / Radzimanowski, J. / Opatowsky, Y.
External linksStructure / PubMed:26365803
MethodsX-ray diffraction
Resolution1.73 - 1.87 Å
Structure data

PDB-4rtt:
Cyrstal structure of SLIT-ROBO Rho GTPase-activating protein 2 fragment
Method: X-RAY DIFFRACTION / Resolution: 1.87 Å

PDB-4rug:
Cyrstal structure of SLIT-ROBO Rho GTPase-activating protein 2 fragment
Method: X-RAY DIFFRACTION / Resolution: 1.73 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / srGAP2 / SH3 / Ligand binding / Robo1 / Nuclear / Plasma Membrane

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