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TitleStructural Basis of Telomerase Inhibition by the Highly Specific BIBR1532.
Journal, issue, pagesStructure, Vol. 23, Page 1934-1942, Year 2015
Publish dateJul 21, 2015 (structure data deposition date)
AuthorsBryan, C. / Rice, C. / Hoffman, H. / Harkisheimer, M. / Sweeney, M. / Skordalakes, E.
External linksStructure / PubMed:26365799
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-5cqg:
Structure of Tribolium telomerase in complex with the highly specific inhibitor BIBR1532
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-55C:
2-{[(2E)-3-(naphthalen-2-yl)but-2-enoyl]amino}benzoic acid

ChemComp-HOH:
WATER

Source
  • tribolium castaneum (red flour beetle)
KeywordsTransferase/Transferase inhibitor / Telomerase Reverse transcriptase fold TERT BIBR15312 / Telomerase Inhibitor / Transferase-Transferase inhibitor complex

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