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TitleMechanistic Basis for the Bypass of a Bulky DNA Adduct Catalyzed by a Y-Family DNA Polymerase.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 137, Page 12131-12142, Year 2015
Publish dateDec 23, 2014 (structure data deposition date)
AuthorsVyas, R. / Efthimiopoulos, G. / Tokarsky, E.J. / Malik, C.K. / Basu, A.K. / Suo, Z.
External linksJ. Am. Chem. Soc. / PubMed:26327169
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-4rzr:
Bypass of a bulky adduct dG1,8 by DPO4
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-DCP:
2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • sulfolobus solfataricus (archaea)
  • synthetic construct (others)
KeywordsTRANSFERASE/DNA / DPO4 / DBH / POLYMERASE / TRANSFERASE-DNA complex

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