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TitleAlpha Beta Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity on Living Cells
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 137, Page 11365-, Year 2015
Publish dateFeb 4, 2015 (structure data deposition date)
AuthorsChecco, J.W. / Lee, E.F. / Evangelista, M. / Sleebs, N. / Rodgers, K. / Pettikiriarachchi, A. / Kershaw, N. / Eddinger, G.A. / Belair, D.G. / Wilson, J.L. ...Checco, J.W. / Lee, E.F. / Evangelista, M. / Sleebs, N. / Rodgers, K. / Pettikiriarachchi, A. / Kershaw, N. / Eddinger, G.A. / Belair, D.G. / Wilson, J.L. / Eller, C.H. / Raines, R.T. / Murphy, W.L. / Smith, B.J. / Gellman, S.H. / Fairlie, W.D.
External linksJ. Am. Chem. Soc. / PubMed:26317395
MethodsX-ray diffraction
Resolution2.24 - 2.695 Å
Structure data

PDB-5agw:
Bcl-2 alpha beta-1 complex
Method: X-RAY DIFFRACTION / Resolution: 2.695 Å

PDB-5agx:
Bcl-2 alpha beta-1 LINEAR complex
Method: X-RAY DIFFRACTION / Resolution: 2.24 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsAPOPTOSIS / BCL-2 / FOLDAMER / BIM

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