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-Structure paper
Title | Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6. |
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Journal, issue, pages | Nat. Struct. Mol. Biol., Vol. 22, Page 703-711, Year 2015 |
Publish date | Aug 17, 2014 (structure data deposition date) |
![]() | Park, E. / Kim, N. / Ficarro, S.B. / Zhang, Y. / Lee, B.I. / Cho, A. / Kim, K. / Park, A.K. / Park, W.Y. / Murray, B. ...Park, E. / Kim, N. / Ficarro, S.B. / Zhang, Y. / Lee, B.I. / Cho, A. / Kim, K. / Park, A.K. / Park, W.Y. / Murray, B. / Meyerson, M. / Beroukhim, R. / Marto, J.A. / Cho, J. / Eck, M.J. |
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Methods | X-ray diffraction |
Resolution | 2.7 - 3.25 Å |
Structure data | ![]() PDB-4r3p: ![]() PDB-4r3r: ![]() PDB-4zjv: |
Chemicals | ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / Kinase / Mig6 / phosphorylation / phophorylation / ATP hydrolysis / TRANSFERASE/INHIBITOR / Epidermal growth factor receptor (EGFR) / ERBB receptor feedback inhibitor 1 / Mitogen-inducible gene 6 protein(Mig6) / TRANSFERASE-INHIBITOR complex |