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| Title | Redesigning a Monospecific Anti-FGFR3 Antibody to Add Selectivity for FGFR2 and Expand Antitumor Activity. |
|---|---|
| Journal, issue, pages | Mol. Cancer Ther., Vol. 14, Page 2270-2278, Year 2015 |
| Publish date | Nov 4, 2014 (structure data deposition date) |
Authors | Yin, Y. / Djakovic, S. / Marsters, S. / Tien, J. / Peng, J. / Tremayne, J. / Lee, G. / Neve, R.M. / Wu, Y. / Merchant, M. ...Yin, Y. / Djakovic, S. / Marsters, S. / Tien, J. / Peng, J. / Tremayne, J. / Lee, G. / Neve, R.M. / Wu, Y. / Merchant, M. / Ashkenazi, A. / Carter, P.J. |
External links | Mol. Cancer Ther. / PubMed:26269606 |
| Methods | X-ray diffraction |
| Resolution | 2.362 Å |
| Structure data | ![]() PDB-4wv1: |
| Chemicals | ![]() ChemComp-HOH: |
| Source |
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Keywords | TRANSFERASE/IMMUNE SYSTEM / FGFR2 / Fab / Complex / Antibody / TRANSFERASE-IMMUNE SYSTEM complex |
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homo sapiens (human)
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