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-Structure paper
Title | N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity. |
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Journal, issue, pages | J. Med. Chem., Vol. 58, Page 7224-7240, Year 2015 |
Publish date | Nov 20, 2014 (structure data deposition date) |
![]() | Nuti, E. / Cantelmo, A.R. / Gallo, C. / Bruno, A. / Bassani, B. / Camodeca, C. / Tuccinardi, T. / Vera, L. / Orlandini, E. / Nencetti, S. ...Nuti, E. / Cantelmo, A.R. / Gallo, C. / Bruno, A. / Bassani, B. / Camodeca, C. / Tuccinardi, T. / Vera, L. / Orlandini, E. / Nencetti, S. / Stura, E.A. / Martinelli, A. / Dive, V. / Albini, A. / Rossello, A. |
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Methods | X-ray diffraction |
Resolution | 1.3 - 1.65 Å |
Structure data | ![]() PDB-4wzv: ![]() PDB-4xct: |
Chemicals | ![]() ChemComp-E40: ![]() ChemComp-ZN: ![]() ChemComp-CA: ![]() ChemComp-EDO: ![]() ChemComp-PGO: ![]() ChemComp-PEG: ![]() ChemComp-AZI: ![]() ChemComp-NA: ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-N73: ![]() ChemComp-DMS: ![]() ChemComp-BUD: |
Source |
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![]() | HYDROLASE / MMP9 Inhibitor complex / Thyroid hormone-binding protein / Inhibitor-complex / metalloprotease |