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TitleEnthalpic Forces Correlate with the Selectivity of Transthyretin-Stabilizing Ligands in Human Plasma.
Journal, issue, pagesJ. Med. Chem., Vol. 58, Page 6507-6515, Year 2015
Publish dateMay 27, 2015 (structure data deposition date)
AuthorsIakovleva, I. / Brannstrom, K. / Nilsson, L. / Gharibyan, A.L. / Begum, A. / Anan, I. / Walfridsson, M. / Sauer-Eriksson, A.E. / Olofsson, A.
External linksJ. Med. Chem. / PubMed:26214366
MethodsX-ray diffraction
Resolution1.75 Å
Structure data

PDB-5boj:
Crystal Structure of Human Transthyretin in Complex with Gemfibrozil
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-4TX:
5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid / medication*YM

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / Thyroxine binding / Gemfibrozil complex

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