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TitleStructural Basis for Ceramide Recognition and Hydrolysis by Human Neutral Ceramidase.
Journal, issue, pagesStructure, Vol. 23, Page 1482-1491, Year 2015
Publish dateSep 18, 2014 (structure data deposition date)
AuthorsAirola, M.V. / Allen, W.J. / Pulkoski-Gross, M.J. / Obeid, L.M. / Rizzo, R.C. / Hannun, Y.A.
External linksStructure / PubMed:26190575
MethodsX-ray diffraction
Resolution2.582 Å
Structure data

PDB-4wgk:
Crystal structure of human neutral ceramidase with Zn-bound phosphate
Method: X-RAY DIFFRACTION / Resolution: 2.582 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-PO4:
PHOSPHATE ION

ChemComp-CIT:
CITRIC ACID

ChemComp-CL:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / ceramidase / amidase / zinc / phosphate

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