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TitleStructural Insights into the Distinct Binding Mode of Cyclic Di-AMP with SaCpaA_RCK.
Journal, issue, pagesBiochemistry, Vol. 54, Page 4936-4951, Year 2015
Publish dateMar 12, 2015 (structure data deposition date)
AuthorsChin, K.H. / Liang, J.M. / Yang, J.G. / Shih, M.S. / Tu, Z.L. / Wang, Y.C. / Sun, X.H. / Hu, N.J. / Liang, Z.X. / Dow, J.M. ...Chin, K.H. / Liang, J.M. / Yang, J.G. / Shih, M.S. / Tu, Z.L. / Wang, Y.C. / Sun, X.H. / Hu, N.J. / Liang, Z.X. / Dow, J.M. / Ryan, R.P. / Chou, S.H.
External linksBiochemistry / PubMed:26171638
MethodsX-ray diffraction
Resolution1.821 - 2.65 Å
Structure data

PDB-4yp1:
Misting with CDA
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

PDB-5f29:
Structure of RCK domain with cda
Method: X-RAY DIFFRACTION / Resolution: 1.821 Å

Chemicals

ChemComp-2BA:
(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • staphylococcus aureus (bacteria)
KeywordsIMMUNE SYSTEM / MSTING / CDA / TRANSPORT PROTEIN / RCK domain / CpaA

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